The following notable locations are found along or adjacent to the route of the Pacific Crest Trail. They are listed from south to north to correspond with the itinerary typically followed by thru-hikers to take advantage of the best seasonal weather conditions. The numbers in parenthesis correspond to the numbers on the PCT overview map above.
California
 Vasquez Rocks |
 Golden Trout Wilderness |
 Sequoia National Park |
 John Muir Wilderness |
 Ansel Adams Wilderness |
 Devils Postpile National Monument |
 Tuolumne Meadows, Yosemite National Park |
 Lassen Volcanic National Park |
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- Campo, California, near the trail's southern terminus at the U.S.-Mexico border
- Anza-Borrego Desert State Park
- Cleveland National Forest
- Big Bear Lake
- Cajon Pass
- Angeles National Forest
- Vasquez Rocks
- Agua Dulce, California
- Walker Pass
- Owens Peak Wilderness
- South Sierra Wilderness
- Golden Trout Wilderness
- Kings Canyon National Park
- Forester Pass, highest point on the trail
- John Muir Wilderness
- Ansel Adams Wilderness
- Devils Postpile National Monument
- Yosemite National Park
- Sonora Pass, Ebbetts Pass, Carson Pass
- Desolation Wilderness
- Lassen National Forest
- Lassen Volcanic National Park
- McArthur-Burney Falls Memorial State Park
- Shasta-Trinity National Forest
- Klamath Mountains
Oregon
 Crater Lake National Park |
 Mount Jefferson and Jefferson Park |
 Three Sisters |
 Santiam Pass |
 Mount Hood Wilderness |
 Bridge of the Gods |
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- Cascade–Siskiyou National Monument
- Rogue River National Forest and Winema National Forest
- Crater Lake National Park
- Umpqua National Forest
- Willamette National Forest and Deschutes National Forest
- Diamond Peak Wilderness
- Waldo Lake
- Three Sisters Wilderness
- Mount Washington Wilderness
- Mount Jefferson Wilderness
- Mount Hood National Forest
- Olallie Scenic Area
- Warm Springs Indian Reservation
- Timberline Lodge
- Mount Hood Wilderness
- Columbia River Gorge National Scenic Area
- Mark O. Hatfield Wilderness (formerly the Columbia Wilderness)
- Cascade Locks, Oregon, lowest point on the trail
- Bridge of the Gods (links Oregon and Washington, crossing the Columbia River)
Washington
 Mount Adams |
 Mount Daniel in the Alpine Lakes Wilderness |
 Glacier Peak Wilderness |
 Cascade Pass in the North Cascades National Park |
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- Gifford Pinchot National Forest
- Indian Heaven Wilderness
- Mount Adams
- Goat Rocks Wilderness
- Mount Rainier National Park
- Mount Baker-Snoqualmie National Forest
- Norse Peak Wilderness
- Alpine Lakes Wilderness
- Henry M. Jackson Wilderness
- Glacier Peak Wilderness
- Snoqualmie Pass
- Stevens Pass
- Lake Chelan National Recreation Area
- Stehekin, Washington, last town along the trail, 10 miles (16 km) from PCT by NPS bus
- North Cascades National Park
- Okanogan National Forest
- Boundary Monument 78, at the Canada – United States border
- British Columbia, Canada
- E.C. Manning Provincial Park, the northern terminus of the trail.
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